Immune-DeficientDrosophila melanogaster: A Model for the Innate Immune Response to Human Fungal Pathogens
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چکیده
منابع مشابه
Immune-deficient Drosophila melanogaster: a model for the innate immune response to human fungal pathogens.
We explored the host-pathogen interactions of the human opportunistic fungus Candida albicans using Drosophila melanogaster. We established that a Drosophila strain devoid of functional Toll receptor is highly susceptible to the human pathogen C. albicans. Using this sensitive strain, we have been able to show that a set of specific C. albicans mutants of different virulence in mammalian infect...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2004
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.172.9.5622